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Aarticaine Hydrochloride / Articaine HCl CAS 23964-57-0 For Anaesthetic Drug

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Aarticaine Hydrochloride / Articaine HCl CAS 23964-57-0 For Anaesthetic Drug

Brand Name : XinRunde
Model Number : 23964-57-0
Certification : GMP
Place of Origin : China(Mainland)
MOQ : 5g
Price : Negotiable
Payment Terms : WU, T/T bank, Bitcoin
Supply Ability : 10 000 KG /month
Delivery Time : 5-7 days after received your payments
Packaging Details : 1-2 kg / aluminum foil bag, 25kg/ drum, as required
Color : White
Alias : Articaine hydrochloride [USAN]; 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2 -(propylamino)propyl)amino)-, methyl ester, monohydrochloride; 4-Methyl-3-(2- (propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl; Articaine HCl; Articaine
Appearance : White Powder
Usage : For Anesthetic Drugs, Pharmaceutical Raw Materials
Type : Pharmaceutical Raw Materials
Delivery : DHL, UPS, Fed Ex, etc
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Aarticaine Hydrochloride / Articaine HCl CAS 23964-57-0 For Anaesthetic Drug



Quick Details:


Product name: Articaine HCl

Synonyms:Articaine hydrochloride [USAN]; 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2
-(propylamino)propyl)amino)-, methyl ester, monohydrochloride; 4-Methyl-3-(2-
(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl; Articaine HCl; Articaine hydrochloride;
Carticaine hydrochloride; HOE 045; HOE 40045; Methyl 4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride; Septanest; Septocaine; UNII-QS9014Q792; Ultracain; Ultracaine; 2-Thiophenecarboxylic acid, 4-methyl-3-(2-(propylamino)propionamido)-, methyl ester, monohydrochloride; Methyl 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-2-thenoate monohydrochloride; methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate hydrochloride (1:1)

MF:C13H20N2O3S.ClH
MW:320.839
EINECS:245-957-7
Assay99%
Quality StandardsEnterprise Standard/Pharma Grade
Appearance:White powder
Packaging Details:25kg/Drum, 1kg/bag
Place of Origin:China



Product Description:


1. Articaine Hydrochloride,Articaine is an intermediate-potency, short-acting amide local anesthetic with a fast metabolism due to an ester group in its structure. It is effective with local infiltration or peripheral nerve block in dentistry, when administered as a spinal, epidural, ocular, or regional nerve block, or when injected intravenously for regional anesthesia.

2. Articaine Hydrochloride, In comparative trials, its clinical effects were not generally significantly different from those of other short-acting local anesthetics like lidocaine, prilocaine, and chloroprocaine, and there is no conclusive evidence demonstrating above-average neurotoxicity. Articaine proved to be suitable and safe for procedures requiring a short duration of action in which a fast onset of anesthesia is desired, eg, dental procedures and ambulatory spinal anesthesia, in normal and in special populations.



Specifications:

Product NameArticaine hydrochloride
CAS23964-57-0Outer Packing25kg
Production Date2016/09/27Shelf life2018/09/26
Standard AdoptedEP 7
Items testedSpecificationResult
DescriptionWhite or almost white crystalline powderWhite crystalline powder
SolubilityFreely soluble in water and in alcoholComplies
IdentificationA,B,C,DComplies
PH4.2-5.24.90
Appearance of solutionSolution should be clearComplies
Related substanceImpurity A ≤0.2%; any other impurity ≤0.1%; Total of other impurities ≤0.5%
Not detected; 0.08%; 0.26%
Heavy metals≤5ppm<5ppm
Loss on drying< 0.5%0.09%
Residue on ignition≤0.1%0.09%
Organic residuecompliescomplies
Assay98.5%-101.0%99.60%
ConclusionQualified



Applications:

1. Articaine Hydrochloride, Articaine blocks nerve conduction by reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, similar to other local anesthetics. Binding of articaine to the sodium channel reduces sodium influx so that the threshold potential will not be reached and impulse conduction stops. The blocking action of articaine on the sodium channel is state dependent: it has the highest affinity for the open state, an intermediate affinity for the inactivated state, and the lowest affinity for the resting state.

2. Articaine Hydrochloride, The degree of neuronal block is affected by the diameter of the nerve. Larger-diameter fibers (touch/pressure/ motor) require higher concentrations of local anesthetic compared with small myelinated fibers (pain afferents).Articaine is lipid soluble, highly protein-bound (94%), and has a dissociation constant (pKa) of 7.8. Articaine is an intermediate-potency, short-acting local anesthetic with a fast onset of action.




Advantages:


Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.

2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.

3. Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4. Warm after-sale service Any of your question would be solved for the first as soon as possible.


Keywords: Articaine HCl / CAS 23964-57-0 / For Anaesthetic Drug



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